TriMix is composed of three ingredients that act synergetically when combined into a sterile injection. These ingredients include Papaverine, Phentolamine and Alprostadil. Each of these ingredients can be indicated for several conditions independently, but they can have highly effective results in treating ED when combined. This combination has become one of the go-to treatment options for men who do not have effective results from conventional PDE5 inhibitors.
Papaverine as a standalone medication is typically prescribed to patients with circulation problems to increase blood flow. As a vasodilator, papaverine relaxes and dilates blood vessels to help blood flow more easily to the heart and throughout the body. In addition, papaverine relaxes smooth muscle within large blood vessels, especially coronary, systemic peripheral and pulmonary arteries, and is almost completely devoid of effects on the central nervous system.
This ingredient is helpful for men struggling with ED because it helps to provide improved circulation to the penis, enabling patients to obtain and maintain a full erection for intercourse.
Phentolamine is a lasting, adrenergic, alpha-receptor blocking agent that enhances blood flow to the skin, mucosa and abdominal viscera and lower blood pressure. Phentolamine works by blocking alpha receptors in the body, which can be found in the muscle that lines the walls of blood vessels. When these alpha receptors are blocked by phentolamine, muscles relax and blood vessels widen, resulting in a substantial increase in blood flow.
Alprostadil can be used to address symptoms of erectile dysfunction in men. Alprostadil, also a vasodilator, is used to relax the muscles and blood vessels in the penis to allow a steady flow of blood to the penis so the user can achieve and maintain an erection. In three different studies conducted on the efficacy and safety of this ingredient used for intracavernosal treatment, it was found that alprostadil is an effective therapy with tolerable side effects.